Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 8/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464180 | 0.80 | ACHE (0.40) | ALDH1A1LMNAUSP2CYP1A2CYP2D6 | |
| SCHEMBL7468270 | 0.80 | MAPT (0.40) | ALDH1A1LMNAMAPK1MAPTKMT2A | |
| SCHEMBL7470671 | 0.79 | SMN1; SMN2 (0.47) | EGFRALDH1A1MAPK1CSF1RPDGFRB | |
| SCHEMBL7472217 | 0.78 | EGFR (0.44) | EGFRLMNACSF1RPDGFRBVCAM1 | |
| SCHEMBL7469896 | 0.77 | EGFR (0.46) | EGFRALDH1A1LMNACSF1RPDGFRB | |
| SCHEMBL7475558 | 0.77 | MAPT (0.43) | ALDH1A1LMNAMAPK1MAPTHTT | |
| SCHEMBL7474845 | 0.75 | LMNA (0.55) | EGFRCLK4ALDH1A1LMNAUSP2 | |
| SCHEMBL7466353 | 0.73 | EGFR (0.47) | EGFRALDH1A1LMNACSF1RPDGFRB | |
| SCHEMBL7462398 | 0.72 | EGFR (0.47) | EGFRALDH1A1LMNAMAPK1PDGFRB | |
| SCHEMBL30275314 | 0.71 | EGFR (0.54) | EGFRALDH1A1LMNACYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |