Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.55 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | CSF1R | P07333 | 5/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462398 | 0.89 | EGFR (0.47) | LMNASMN1; SMN2PIK3CDPIK3R1HTT | |
| SCHEMBL7472729 | 0.87 | EGFR (0.45) | LMNASMN1; SMN2PIK3CDPIK3R1HTT | |
| SCHEMBL8825693 | 0.83 | LMNA (0.51) | LMNASMN1; SMN2PIK3CDPIK3R1HTT | |
| SCHEMBL7469735 | 0.79 | LMNA (0.47) | LMNASMN1; SMN2PIK3CDPIK3R1HTT | |
| SCHEMBL7466353 | 0.78 | EGFR (0.47) | LMNASMN1; SMN2CSF1REGFRALDH1A1 | |
| SCHEMBL7470671 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2HTTCSF1REGFRALDH1A1 | |
| SCHEMBL12459324 | 0.77 | LMNA (0.73) | LMNASMN1; SMN2PIK3CDPIK3R1HTT | |
| SCHEMBL7469896 | 0.76 | EGFR (0.46) | LMNACSF1REGFRALDH1A1MAPT | |
| SCHEMBL7475194 | 0.75 | EGFR (0.66) | LMNASMN1; SMN2HTTEGFRRAB9A | |
| SCHEMBL7472217 | 0.75 | EGFR (0.44) | LMNACSF1REGFRMAPTPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |