Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.46 |
| ▸ | CSF1R | P07333 | 7/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470671 | 0.81 | SMN1; SMN2 (0.47) | EGFRCSF1RALDH1A1MAPTPDGFRB | |
| SCHEMBL7470183 | 0.80 | MAPT (0.42) | ALDH1A1MAPTLMNASIGMAR1 | |
| SCHEMBL7472217 | 0.77 | EGFR (0.44) | EGFRCSF1RMAPTPDGFRBLMNA | |
| SCHEMBL7467291 | 0.77 | EGFR (0.44) | EGFRCSF1RALDH1A1MAPTPDGFRB | |
| SCHEMBL7474845 | 0.76 | LMNA (0.55) | EGFRCSF1RALDH1A1MAPTPDGFRB | |
| SCHEMBL7466353 | 0.74 | EGFR (0.47) | EGFRCSF1RALDH1A1MAPTPDGFRB | |
| SCHEMBL7462398 | 0.73 | EGFR (0.47) | EGFRPIN1ALDH1A1MAPTPDGFRB | |
| SCHEMBL7472729 | 0.72 | EGFR (0.45) | EGFRPIN1ALDH1A1MAPTPDGFRB | |
| SCHEMBL7469892 | 0.72 | EGFR (0.55) | EGFRALDH1A1 | |
| SCHEMBL30275314 | 0.70 | EGFR (0.54) | EGFRALDH1A1MAPTPDGFRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |