Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465790 | 0.92 | VNN1 (0.35) | HTTHSD17B10MAPK14SRD5A2 | |
| SCHEMBL7479804 | 0.83 | GLA (0.38) | GLAHPGDCNR2CNR1F2 | |
| SCHEMBL7470913 | 0.83 | HTT (0.41) | HTTHSD17B10GLAHPGDMAPT | |
| SCHEMBL7475914 | 0.82 | MAPK14 (0.41) | HTTHSD17B10GLAHPGDMAPK14 | |
| SCHEMBL7468553 | 0.81 | MAPK14 (0.45) | HTTHSD17B10GLAMAPK14MAPT | |
| SCHEMBL7476794 | 0.81 | HSD17B10 (0.41) | HTTHSD17B10GLAHPGDMAPT | |
| SCHEMBL7463562 | 0.78 | NR1H2 (0.47) | HTTHSD17B10GLAHPGDMAPT | |
| SCHEMBL7475152 | 0.77 | MAPK14 (0.44) | HTTHSD17B10HPGDMAPK14MAPT | |
| SCHEMBL7478826 | 0.75 | VNN1 (0.35) | MAPTLMNAP2RX1 | |
| SCHEMBL7473148 | 0.74 | MAPK14 (0.44) | MAPK14MAPTLMNATSHRTNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077701-A4 | ANTI-VIRAL COMPOUNDS | LILLY CO ELI (US) | 2002-03-20 | — | — | EP | disclosed |
| EP-1077701-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059587-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-11-25 | — | — | WO | disclosed |