Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478826 | 0.92 | VNN1 (0.35) | ABCC9ABCC8KCNJ11KCNJ8P2RX1 | |
| SCHEMBL7468466 | 0.85 | ABCC9 (0.38) | ABCC9ABCC8KCNJ11KCNJ8DHODH | |
| SCHEMBL7472346 | 0.84 | LMNA (0.36) | GLAHPGDABCC9ABCC8KCNJ11 | |
| SCHEMBL7470675 | 0.83 | HTT (0.41) | GLAHPGDP2RX1CNR2CNR1 | |
| SCHEMBL7479307 | 0.82 | GLA (0.39) | GLAHPGDP2RX1POLBCNR2 | |
| SCHEMBL7476080 | 0.81 | ABCC9 (0.39) | GLAHPGDABCC9ABCC8KCNJ11 | |
| SCHEMBL7478724 | 0.78 | PDK1 (0.40) | GLAHPGDDHODHPOLBNR3C2 | |
| SCHEMBL7472543 | 0.78 | ABCC9 (0.38) | GLAHPGDABCC9ABCC8KCNJ11 | |
| SCHEMBL7474253 | 0.78 | ABCC9 (0.36) | ABCC9ABCC8KCNJ11KCNJ8DHODH | |
| SCHEMBL7473084 | 0.76 | ABCC9 (0.34) | GLAHPGDABCC9ABCC8KCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077701-A4 | ANTI-VIRAL COMPOUNDS | LILLY CO ELI (US) | 2002-03-20 | — | — | EP | disclosed |
| EP-1077701-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059587-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-11-25 | — | — | WO | disclosed |