Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 18/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466273 | 0.92 | PDE5A (0.57) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7468674 | 0.90 | PDE5A (0.57) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7473397 | 0.90 | PDE5A (0.59) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7466788 | 0.88 | PDE5A (0.57) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7465985 | 0.87 | PDE5A (0.55) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7473166 | 0.85 | HTR6 (0.55) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7469571 | 0.85 | EGFR (0.56) | PDE5AALDH1A1SMN1; SMN2 | |
| SCHEMBL7468592 | 0.85 | PDE5A (0.52) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7475093 | 0.82 | PDE5A (0.68) | PDE5AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7459991 | 0.81 | LMNA (0.52) | MEN1KMT2AALDH1A1CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |