Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SCN4A | P35499 | 2/20 | 0.44 |
| ▸ | PRCP | P42785 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474472 | 0.92 | S1PR1 (0.46) | HRH3MCHR1DRD4MMP3S1PR1 | |
| SCHEMBL7477194 | 0.88 | DRD4 (0.59) | DRD4MMP3DRD2MAPT | |
| SCHEMBL7462774 | 0.82 | S1PR1 (0.49) | HRH3MMP3S1PR1DRD2 | |
| SCHEMBL7464080 | 0.80 | DRD4 (0.55) | DRD4MMP3DRD2MAPT | |
| SCHEMBL7465032 | 0.78 | S1PR1 (0.48) | HRH3MMP3S1PR1BCHETP53 | |
| SCHEMBL12041705 | 0.77 | HRH3 (0.55) | HRH3MMP3S1PR1DRD2PRCP | |
| SCHEMBL12041706 | 0.77 | S1PR1 (0.69) | HRH3MMP3S1PR1DRD2PRCP | |
| SCHEMBL381548 | 0.76 | S1PR1 (0.67) | HRH3MMP3S1PR1DRD2PRCP | |
| SCHEMBL7470302 | 0.75 | MEN1 (0.60) | DRD4MMP3DRD2MAPT | |
| SCHEMBL6159068 | 0.74 | DRD2 (0.81) | HRH3MCHR1DRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757986-B1 | Arylpiperidine and arylpiperazine derivatives and drugs containing the same | SUNTORY LTD (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-5723475-A | Arylpiperidine and arylpiperazine derivatives and medicament containing the same | SUNTORY LIMITED (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0757986-A1 | ARYLPIPERIDINE AND ARYLPIPERAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-02-12 | — | — | EP | disclosed |