Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SCN4A | P35499 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470932 | 0.92 | HRH3 (0.49) | S1PR1DRD2HRH3MCHR1DRD4 | |
| SCHEMBL7464080 | 0.89 | DRD4 (0.55) | DRD2DRD4MMP3 | |
| SCHEMBL7462774 | 0.87 | S1PR1 (0.49) | S1PR1DRD2HRH3MMP3 | |
| SCHEMBL7465032 | 0.84 | S1PR1 (0.48) | S1PR1HRH3MMP3 | |
| SCHEMBL7477194 | 0.80 | DRD4 (0.59) | DRD2DRD4MMP3 | |
| SCHEMBL7476550 | 0.75 | DRD2 (0.55) | DRD2 | |
| SCHEMBL7471366 | 0.73 | CACNA1G (0.53) | DRD2 | |
| SCHEMBL12041705 | 0.72 | HRH3 (0.55) | S1PR1DRD2HRH3MMP3 | |
| SCHEMBL12041706 | 0.72 | S1PR1 (0.69) | S1PR1DRD2HRH3MMP3 | |
| SCHEMBL6161610 | 0.72 | SIGMAR1 (0.76) | S1PR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757986-B1 | Arylpiperidine and arylpiperazine derivatives and drugs containing the same | SUNTORY LTD (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-5723475-A | Arylpiperidine and arylpiperazine derivatives and medicament containing the same | SUNTORY LIMITED (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0757986-A1 | ARYLPIPERIDINE AND ARYLPIPERAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-02-12 | — | — | EP | disclosed |