SCHEMBL747100

SCHEMBL747100

CCC1COC(c2ccccc2)(C(O)c2ccccc2)O1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 12/20 0.37
HTR1A P08908 10/20 0.37
ADRA1D P25100 10/20 0.37
ADRA1B P35368 10/20 0.37
CHRM2 P08172 3/20 0.35
CHRM4 P08173 3/20 0.35
CHRM5 P08912 3/20 0.35
CHRM1 P11229 3/20 0.35
CHRM3 P20309 3/20 0.35
LMNA P02545 1/20 0.35
OPRM1 P35372 1/20 0.33
OPRD1 P41143 1/20 0.33
OPRK1 P41145 1/20 0.33
OPRL1 P41146 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL749051 0.91 HTR1A (0.36) ADRA1AHTR1AADRA1DADRA1BCHRM2
SCHEMBL747277 0.89 PTGS2 (0.37) ADRA1AHTR1AADRA1DADRA1BCHRM2
SCHEMBL748893 0.88 OPRM1 (0.35) ADRA1AHTR1AADRA1DADRA1BOPRM1
SCHEMBL747694 0.88 ALDH1A1 (0.36) ADRA1AHTR1AADRA1DADRA1BCHRM2
SCHEMBL750087 0.87 OPRM1 (0.36) ADRA1AHTR1AADRA1DADRA1BOPRM1
SCHEMBL751247 0.86 HTR1A (0.37) ADRA1AHTR1AADRA1DADRA1B
SCHEMBL747690 0.86 OPRM1 (0.37) ADRA1AHTR1AADRA1DADRA1BOPRM1
SCHEMBL749059 0.84 HTR1A (0.33) ADRA1AHTR1AADRA1DADRA1BLMNA
SCHEMBL750056 0.84 HTR1A (0.35) ADRA1AHTR1AADRA1DADRA1BCHRM2
Methyl Alcohol SCHEMBL3692825 0.83 HTR1A (0.34) ADRA1AHTR1AADRA1DADRA1BCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2452984-A1 Degassing Compositions for Curable Coatings Troy Technology Corporation, Inc. (US) 2012-05-16 EP claimed
EP-2152812-B1 DEGASSING COMPOSITIONS FOR CURABLE COATINGS TROY TECHNOLOGY CORP INC (US) 2012-03-21 EP claimed
US-7615585-B2 Degassing compositions for curable coatings TROY CORPORATION (US) 2009-11-10 US claimed
US-20090023847-A1 Degassing compositions for curable coatings TROY CORPORATION 2009-01-22 US claimed
EP-2452984-A1 Degassing Compositions for Curable Coatings Troy Technology Corporation, Inc. (US) 2012-05-16 EP disclosed
EP-2152812-B1 DEGASSING COMPOSITIONS FOR CURABLE COATINGS TROY TECHNOLOGY CORP INC (US) 2012-03-21 EP disclosed
US-7842745-B2 Degassing compositions for curable coatings TROY CORPORATION (US) 2010-11-30 US disclosed
US-7842745-B2 Degassing compositions for curable coatings TROY CORPORATION (US) 2010-11-30 US disclosed
US-7842745-B2 Degassing compositions for curable coatings TROY CORPORATION (US) 2010-11-30 US disclosed
US-20100204373-A1 Degassing compositions for curable coatings TROY CORPORATION 2010-08-12 US disclosed
US-20100204373-A1 Degassing compositions for curable coatings TROY CORPORATION 2010-08-12 US disclosed
US-20100204373-A1 Degassing compositions for curable coatings TROY CORPORATION 2010-08-12 US disclosed
EP-2152812-A1 DEGASSING COMPOSITIONS FOR CURABLE COATINGS Troy Technology Corporation, Inc. (US) 2010-02-17 EP disclosed
US-7615585-B2 Degassing compositions for curable coatings TROY CORPORATION (US) 2009-11-10 US disclosed
US-7615585-B2 Degassing compositions for curable coatings TROY CORPORATION (US) 2009-11-10 US disclosed
US-20090023847-A1 Degassing compositions for curable coatings TROY CORPORATION 2009-01-22 US disclosed
US-20090023847-A1 Degassing compositions for curable coatings TROY CORPORATION 2009-01-22 US disclosed
WO-2008130538-A1 DEGASSING COMPOSITIONS FOR CURABLE COATINGS TROY TECHNOLOGY CORPORATION, INC. (US) 2008-10-30 WO disclosed