Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 2/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | EYA2 | O00167 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21479581 | 0.81 | ALOX5 (0.50) | ALOX5LMNAKDM5APHF8KDM2A | |
| SCHEMBL21582620 | 0.79 | ALOX5 (0.48) | ALOX5LMNAKDM5APHF8KDM2A | |
| SCHEMBL4668913 | 0.78 | ALOX5 (0.48) | ALOX5HDAC1HDAC6LMNACYP2D6 | |
| SCHEMBL20018429 | 0.77 | ALOX5 (0.47) | ALOX5LMNAEYA2APPACE | |
| SCHEMBL6680983 | 0.77 | CTSK (0.37) | ALOX5HDAC1HDAC6LMNAKDM5A | |
| SCHEMBL2810316 | 0.74 | CTSS (0.35) | ALOX5LMNAEPHX1 | |
| SCHEMBL9464496 | 0.73 | ALOX5 (0.34) | ALOX5HDAC1HDAC6 | |
| SCHEMBL8773484 | 0.73 | HDAC1 (0.61) | HDAC1HDAC6LMNA | |
| SCHEMBL7760755 | 0.72 | ALOX5 (0.67) | ALOX5HDAC1HDAC6CYP2D6EPHX1 | |
| SCHEMBL21242212 | 0.72 | TDP1 (0.48) | ALOX5LMNAEYA2APPACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871619-B1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMA (US) | 2002-11-06 | — | — | EP | disclosed |
| US-6458959-B1 | VIRICIDES AND ENZYME INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-10-01 | — | — | US | disclosed |
| US-6348477-B1 | SUBSTITUTED PHENYL THIAZOLE DERIVATIVES AS VIRICIDES | BOEHRINGER INGELHEIM(CANADA) LTD. (CA) | 2002-02-19 | — | — | US | disclosed |
| US-6288091-B1 | COMPOUNDS SUCH AS 2,2,2-TRICHLOROETHYL N-(4-(2-AMINO-4-THIAZOLYL)-PHENYL)CARBAMATE THAT INHIBIT THE HERPES HELCASE-PRIMASE ENZYME COMPLEX | BOEHRINGER INGELHEIM LTD. (CA) | 2001-09-11 | — | — | US | disclosed |
| US-6057451-A | AMINOTHIAZOLE DERIVATIVES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-05-02 | — | — | US | disclosed |
| EP-0871619-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997024343-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1997-07-10 | — | — | WO | disclosed |