Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.67 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3124936 | 0.83 | ALOX5 (0.53) | ALOX5EPHX1HDAC1HDAC6 | |
| SCHEMBL3115065 | 0.81 | ALOX5 (0.52) | ALOX5EPHX1 | |
| SCHEMBL9308624 | 0.80 | ALOX5 (1.00) | ALOX5EPHX1CYP2D6 | |
| SCHEMBL9307728 | 0.80 | ALOX5 (1.00) | ALOX5EPHX1CYP2D6 | |
| SCHEMBL3567122 | 0.78 | ALOX5 (0.62) | ALOX5EPHX1CYP2D6HPGDKMT2A | |
| SCHEMBL9308307 | 0.77 | ALOX5 (1.00) | ALOX5EPHX1 | |
| SCHEMBL3986170 | 0.74 | ALOX5 (0.48) | ALOX5EPHX1 | |
| SCHEMBL9308267 | 0.73 | ALOX5 (1.00) | ALOX5EPHX1PARP15PARP10 | |
| SCHEMBL7471043 | 0.72 | ALOX5 (0.50) | ALOX5EPHX1CYP2D6HDAC1HDAC6 | |
| SCHEMBL20343561 | 0.72 | ALOX5 (0.47) | ALOX5CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104422-A1 | PHENYL XANTHINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000009507-A1 | PHENYL YANTHINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-02-24 | — | — | WO | disclosed |