Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | F3 | P13726 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471186 | 0.82 | KMT2A (0.47) | KMT2AGAAHSD17B10ATMACACB | |
| SCHEMBL6876523 | 0.80 | L3MBTL1 (0.40) | GAAATMACACBKDM4EHPGD | |
| SCHEMBL6762666 | 0.77 | ALDH1A1 (0.34) | KMT2AGAAHSD17B10MEN1KDM4E | |
| SCHEMBL6757871 | 0.69 | SMN1; SMN2 (0.38) | KMT2AGAAHSD17B10MEN1KDM4E | |
| SCHEMBL6760029 | 0.69 | RAB9A (0.40) | KMT2AGAAHSD17B10MEN1KDM4E | |
| SCHEMBL159472 | 0.67 | KMT2A (0.63) | KMT2AGAAHSD17B10ATMACACB | |
| SCHEMBL27727377 | 0.65 | GAA (0.87) | KMT2AGAAHSD17B10ATMACACB | |
| SCHEMBL31055430 | 0.64 | KMT2A (0.78) | KMT2AGAAHSD17B10ATMMEN1 | |
| SCHEMBL7090374 | 0.64 | GAA (0.78) | KMT2AGAAHSD17B10ATMACACB | |
| SCHEMBL6876519 | 0.64 | L3MBTL1 (0.44) | KMT2AGAAHSD17B10ATMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001068605-A1 | POLYCYCLIC ARYL AND HETEROARYL SUBSTITUTED BENZENES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-09-20 | — | — | WO | claimed |