Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27626385 | 0.83 | CA12 (0.50) | ALDH1A1HPGDKDM4ENPSR1ERN1 | |
| SCHEMBL7616763 | 0.83 | KDM4E (0.54) | ALDH1A1HPGDKDM4ENPSR1ERN1 | |
| SCHEMBL10560587 | 0.82 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4ENPSR1ERN1 | |
| SCHEMBL27697072 | 0.81 | CTSD (0.50) | ALDH1A1HPGDKDM4ENPSR1ERN1 | |
| SCHEMBL9752925 | 0.79 | FFAR1 (0.44) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL8967497 | 0.78 | KDM4E (0.51) | ALDH1A1HPGDKDM4ENPSR1L3MBTL1 | |
| SCHEMBL2770226 | 0.78 | KDM4E (0.42) | ALDH1A1HPGDKDM4ENPSR1ERN1 | |
| SCHEMBL29777535 | 0.78 | KDM4E (0.42) | ALDH1A1HPGDKDM4ENPSR1ERN1 | |
| SCHEMBL10783071 | 0.77 | HPGD (0.43) | ALDH1A1HPGDKDM4ENPSR1ERN1 | |
| SCHEMBL14134452 | 0.76 | CYP1A2 (0.45) | ALDH1A1HPGDKDM4ENPSR1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222174-A1 | IMIDAZOL-4-YLMETHANOLS USED AS INHIBITORS OF STEROID C17-20 LYASE | Takeda Chemical Industries, Ltd. (JP) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001030762-A1 | IMIDAZOL-4-YLMETHANOLS USE AS INHIBITORS OF STEROID C17-20 LYASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |