Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2150320 | 0.80 | USP2 (0.55) | FFAR1CYP3A4MAPK1USP2SMN1; SMN2 | |
| SCHEMBL7471611 | 0.79 | ALDH1A1 (0.44) | CYP3A4MAPTALDH1A1TUBB1HTT | |
| SCHEMBL5720437 | 0.78 | FFAR1 (0.42) | FFAR1CYP3A4MAPK1USP2SMN1; SMN2 | |
| SCHEMBL11420620 | 0.78 | CYP3A4 (0.67) | FFAR1CYP3A4MAPK1MAPTUSP2 | |
| SCHEMBL4220772 | 0.78 | FFAR1 (0.52) | FFAR1CYP3A4MAPK1MAPTUSP2 | |
| SCHEMBL9752827 | 0.77 | CYP3A4 (0.60) | CYP3A4MAPK1MAPTUSP2SMN1; SMN2 | |
| SCHEMBL8213079 | 0.76 | MAPK1 (0.54) | CYP3A4MAPK1MAPTTPMTALDH1A1 | |
| SCHEMBL3701446 | 0.75 | HIF1A (0.53) | ALDH1A1KDM4E | |
| SCHEMBL9714676 | 0.74 | MAPT (0.49) | MAPK1MAPTSMN1; SMN2ALDH1A1TUBB1 | |
| SCHEMBL14519857 | 0.73 | CA12 (0.61) | CYP3A4MAPK1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009595-A1 | ANTI-VIRAL COMPOSITIONS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-07-11 | — | — | WO | disclosed |