Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7579266 | 0.88 | MAPT (0.47) | MAPTTSHRRECQLNPSR1ADAM17 | |
| SCHEMBL7474692 | 0.78 | AGTR1 (0.43) | ADAM17AGTR1AGTR2 | |
| SCHEMBL1564276 | 0.78 | HTT (0.59) | MAPTADAM17STAT3HTTSMN1; SMN2 | |
| SCHEMBL7410625 | 0.75 | ADAM17 (0.42) | MAPTTSHRRECQLNPSR1ADAM17 | |
| SCHEMBL7410622 | 0.75 | ADAM17 (0.42) | MAPTTSHRRECQLNPSR1ADAM17 | |
| SCHEMBL7419501 | 0.73 | AGTR1 (0.42) | MAPTTSHRRECQLNPSR1ADAM17 | |
| SCHEMBL7419504 | 0.73 | ADAM17 (0.41) | MAPTTSHRRECQLNPSR1ADAM17 | |
| SCHEMBL9178138 | 0.72 | AGTR1 (0.63) | AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL9175717 | 0.70 | ADAM17 (0.52) | ADAM17AGTR1AGTR2 | |
| SCHEMBL7466358 | 0.69 | AGTR1 (0.44) | ADAM17AGTR1AGTR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016071-A1 | HETEROCYCLIC DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-19 | — | — | WO | disclosed |