Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468941 | 0.85 | PDE4B (0.40) | ALDH1A1TSHRSQORPDE4BHTT | |
| SCHEMBL7466427 | 0.84 | APP (0.42) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL7472131 | 0.83 | CYP2A6 (0.47) | ALDH1A1NPC1HPGDTSHRRAB9A | |
| SCHEMBL7355495 | 0.81 | HPRT1 (0.38) | ALDH1A1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7458288 | 0.80 | HSD11B1 (0.40) | TSHRMAPT | |
| SCHEMBL6991078 | 0.78 | SQOR (0.41) | ALDH1A1SQORPDE4BHTTPDE4A | |
| SCHEMBL7470694 | 0.77 | SQOR (0.40) | ALDH1A1HPGDSQORPDE4BPDE4A | |
| SCHEMBL7467257 | 0.76 | TOP1 (0.41) | NPC1RAB9ASMN1; SMN2CYP2B6CYP1A2 | |
| SCHEMBL10415463 | 0.76 | MAPT (0.41) | ALDH1A1NPC1HPGDTSHRRAB9A | |
| SCHEMBL4439979 | 0.75 | ALDH1A1 (0.42) | ALDH1A1NPC1RAB9ASMN1; SMN2FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | claimed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | claimed |