Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.36 |
| ▸ | PDE4A | P27815 | 4/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468941 | 0.92 | PDE4B (0.40) | PDE4BPDE4APDE4CPDE4DMEN1 | |
| SCHEMBL7470694 | 0.86 | SQOR (0.40) | PDE4BPDE4APDE4CPDE4DMEN1 | |
| SCHEMBL10415463 | 0.85 | MAPT (0.41) | PDE4BPDE4APDE4CPDE4DNPC1 | |
| SCHEMBL7471844 | 0.81 | ALDH1A1 (0.35) | PDE4BPDE4APDE4CPDE4DNPC1 | |
| SCHEMBL7467257 | 0.79 | TOP1 (0.41) | NPC1RAB9ATDP1NFKB1NFKB2 | |
| SCHEMBL9955938 | 0.79 | PTGS2 (0.36) | NPC1RAB9AMEN1KMT2ASQOR | |
| SCHEMBL6991078 | 0.78 | SQOR (0.41) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL7466427 | 0.78 | APP (0.42) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4439979 | 0.78 | ALDH1A1 (0.42) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7467196 | 0.78 | PDGFRB (0.35) | PDE4BPDE4APDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091945-A1 | CYCLIC CARBAMATES AND ISOXAZOLIDINES AS IIB/IIIA ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000000481-A1 | CYCLIC CARBAMATES AND ISOXAZOLIDINES AS IIB/IIIA ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-01-06 | — | — | WO | disclosed |