Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.43 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.40 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.40 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1928824 | 0.88 | PLAAT3 (0.51) | TDP1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL18657080 | 0.83 | CYP4Z1 (0.49) | TDP1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL6754911 | 0.83 | IGF1R (0.48) | TDP1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL7415485 | 0.82 | TSHR (0.56) | TDP1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL18373121 | 0.82 | HPGD (0.50) | TDP1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL16672973 | 0.82 | HPGD (0.50) | TDP1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL22921868 | 0.81 | TSHR (0.58) | ALDH1A1EPHX2CYP4Z1CYP4F11CYP4F12 | |
| SCHEMBL2569441 | 0.78 | L3MBTL1 (0.55) | TDP1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL23843382 | 0.77 | POLB (0.54) | ALDH1A1 | |
| SCHEMBL9235577 | 0.77 | L3MBTL1 (0.55) | TDP1PLAAT3PLAAT5PLAAT2PLAAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002022113-A2 | RETINOIC ACID RECEPTOR ANTAGONISTS AS PROMOTERS OF ANGIOGENESIS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-03-21 | — | — | WO | disclosed |
| EP-1173061-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF HYPERPROLIFERATIVE DISEASES | Bristol-Myers Squibb Company (US) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064260-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF HYPERPROLIFERATIVE DISEASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-11-02 | — | — | WO | disclosed |