Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL905940 | 0.83 | RAB9A (0.44) | RAB9ANPC1KDM4EPABPC1PKM | |
| SCHEMBL905938 | 0.78 | HTR2C (0.36) | RAB9AKDM4EHTTALDH1A1MEN1 | |
| SCHEMBL10199630 | 0.78 | HTT (0.37) | RAB9ANPC1KDM4EPABPC1PKM | |
| SCHEMBL7467529 | 0.77 | HTR6 (0.47) | CHRM2HTR1ACHRM5ADRA2ADRD2 | |
| Fumaric Acid SCHEMBL6626914 | 0.74 | FABP4 (0.40) | RAB9ANPC1KDM4EPABPC1PKM | |
| Fumaric Acid SCHEMBL6626910 | 0.70 | NPSR1 (0.38) | KDM4EALDH1A1NPSR1MEN1KMT2A | |
| Fumaric Acid SCHEMBL6626918 | 0.70 | NPSR1 (0.38) | KDM4EALDH1A1NPSR1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL905957 | 0.70 | HTT (0.42) | RAB9ANPC1KDM4EPABPC1PKM | |
| Ammonia Solution, Strong SCHEMBL905923 | 0.69 | RAB9A (0.40) | RAB9ANPC1KDM4EPABPC1PKM | |
| SCHEMBL4026317 | 0.69 | SCARB1 (0.46) | KDM4EALDH1A1MEN1KMT2ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202965-A1 | INDOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR MEDICINAL APPLICATION | VERNALIS RESEARCH LIMITED (GB) | 2002-05-08 | — | — | EP | claimed |
| WO-2001012603-A1 | INDOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR MEDICINAL APPLICATION | VERNALIS RESEARCH LIMITED (GB) | 2001-02-22 | — | — | WO | claimed |