Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 12/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7476207 | 0.84 | GABRA1 (0.58) | ALOX5GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL7478300 | 0.81 | GABRA1 (0.52) | ALOX5GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL7477511 | 0.78 | ALOX5 (0.48) | ALOX5GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL3985463 | 0.75 | KDM4E (0.71) | ALOX5GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL7826782 | 0.74 | ALOX5 (0.81) | ALOX5GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL25904050 | 0.73 | GAA (0.53) | ALOX5GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL7826833 | 0.73 | GAA (0.75) | ALOX5GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL6796057 | 0.71 | ALOX5 (0.76) | ALOX5GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL3988373 | 0.71 | KDM4E (0.68) | ALOX5GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL28750014 | 0.70 | TSHR (0.50) | GAAKDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1379774-A | Compounds | ASTRAZENECA AB (SE) | 2002-11-13 | — | — | CN | disclosed |
| EP-1210343-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | AstraZeneca AB (SE) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001012187-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2001-02-22 | — | — | WO | disclosed |