Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28750014 | 0.88 | TSHR (0.50) | KDM4EALDH1A1GAAHPGDLMNA | |
| SCHEMBL7481382 | 0.87 | ALDH1A1 (0.46) | KDM4EALDH1A1GAAHPGDLMNA | |
| SCHEMBL7469855 | 0.87 | GABRA1 (0.46) | KDM4EALDH1A1GAAHPGDLMNA | |
| SCHEMBL7474003 | 0.86 | HRH3 (0.60) | KDM4EALDH1A1GAAHPGDLMNA | |
| SCHEMBL7477279 | 0.85 | PDGFRB (0.49) | KDM4EALDH1A1GAAHPGDLMNA | |
| SCHEMBL7478060 | 0.84 | CYP11B1 (0.43) | KDM4EALDH1A1GAAHPGDLMNA | |
| SCHEMBL7481943 | 0.84 | SMN1; SMN2 (0.46) | KDM4EALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL7482853 | 0.83 | HRH3 (0.50) | KDM4EALDH1A1GAAHPGDLMNA | |
| SCHEMBL7471932 | 0.79 | HSD17B10 (0.39) | KDM4EALDH1A1GAAHPGDLMNA | |
| SCHEMBL7472435 | 0.78 | ALOX5 (0.64) | ALOX5KDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210343-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | AstraZeneca AB (SE) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001012187-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2001-02-22 | — | — | WO | disclosed |