Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465809 | 0.87 | AKR1C3 (0.36) | MAPTMAPK8PTGDR2MAT2AMEN1 | |
| Iodide SCHEMBL7464172 | 0.86 | GAA (0.35) | GAAALDH1A1KDM4EGLAHPGD | |
| SCHEMBL7468725 | 0.84 | HTT (0.38) | GAAALDH1A1KDM4EHPGDUSP2 | |
| SCHEMBL7457272 | 0.83 | NOD1 (0.37) | ALDH1A1KDM4EHPGDUSP2NPSR1 | |
| SCHEMBL7468036 | 0.83 | NOD1 (0.39) | GAAALDH1A1KDM4EHPGDPTGDR2 | |
| SCHEMBL7467186 | 0.82 | NOD1 (0.36) | MAPTGAAALDH1A1KDM4EHPGD | |
| SCHEMBL7460791 | 0.81 | TP53 (0.39) | MAPTGAAALDH1A1KDM4EHPGD | |
| SCHEMBL7463805 | 0.80 | KMT2A (0.40) | MAPTGAAALDH1A1PTGDR2MAT2A | |
| SCHEMBL7472637 | 0.79 | MEN1 (0.40) | MAPTGAAALDH1A1KDM4ETSHR | |
| SCHEMBL8705102 | 0.79 | GAA (0.38) | MAPTGAAKDM4EHPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |