Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465813 | 0.88 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1LMNAMAPT | |
| Iodide SCHEMBL7464178 | 0.85 | MAPT (0.37) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL7468729 | 0.85 | MAPT (0.46) | MEN1KMT2ALMNAMAPTTSHR | |
| SCHEMBL7467945 | 0.84 | AKR1B1 (0.39) | MAPTSMN1; SMN2GAA | |
| SCHEMBL7457276 | 0.84 | MAPT (0.47) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL7468043 | 0.83 | MAPT (0.48) | MEN1KMT2ALMNAMAPTTSHR | |
| SCHEMBL7467191 | 0.82 | L3MBTL1 (0.45) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL7460793 | 0.81 | MAPT (0.51) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL7460868 | 0.80 | GAA (0.36) | MAPTSMN1; SMN2L3MBTL1GAATDP1 | |
| SCHEMBL7463809 | 0.80 | TP53 (0.51) | ALDH1A1LMNAMAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |