Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.46 |
| ▸ | PPARA | Q07869 | 13/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 11/20 | 0.46 |
| ▸ | PTGES | O14684 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL7462413 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTTDP1LTA4H | |
| SCHEMBL6932774 | 0.80 | MMP9 (0.60) | PPARGPPARAALOX5PTGESALDH1A1 | |
| Hydroxyamine SCHEMBL7467048 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTTDP1LTA4H | |
| Hydroxyamine SCHEMBL7409029 | 0.76 | ACACB (0.41) | PPARGPPARAALOX5PTGESSMN1; SMN2 | |
| Hydroxyamine SCHEMBL7380672 | 0.75 | PPARG (0.52) | PPARGPPARAALOX5PTGESSMN1; SMN2 | |
| Hydroxyamine SCHEMBL7381106 | 0.71 | PPARG (0.40) | PPARGPPARAALOX5PTGES | |
| SCHEMBL9613848 | 0.69 | PPARG (0.81) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL19234906 | 0.68 | LTA4H (0.60) | ALDH1A1KDM4EMAPTTDP1LTA4H | |
| SCHEMBL19234891 | 0.68 | LTA4H (0.60) | ALDH1A1KDM4EMAPTTDP1LTA4H | |
| SCHEMBL9857889 | 0.66 | PPARG (0.74) | PPARGPPARAALOX5PTGESALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970046-A1 | N-HYDROXY-2-(ALKYL, ARYL, OR HETEROARYL SULFANYL, SULFINYL OR SULFONYL)-3-SUBSTITUTED ALKYL, ARYL OR HETEROARYLAMIDES AS MATRIX METALLOPROTEINASE INHIBITORS | American Cyanamid Company (US) | 2000-01-12 | — | — | EP | claimed |
| WO-1998038163-A1 | N-HYDROXY-2-(ALKYL, ARYL, OR HETEROARYL SULFANYL, SULFINYL OR SULFONYL)-3-SUBSTITUTED ALKYL, ARYL OR HETEROARYLAMIDES AS MATRIX METALLOPROTEINASE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1998-09-03 | — | — | WO | claimed |