Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470489 | 0.84 | EPHX2 (0.47) | EPHX1EPHX2ALDH1A1PDE2AKMT2A | |
| SCHEMBL28519919 | 0.84 | EPHX1 (0.51) | EPHX1EPHX2SCN10AALDH1A1PDE2A | |
| SCHEMBL7470004 | 0.81 | TRPM8 (0.49) | EPHX1ALDH1A1GAAMAPTSCN9A | |
| SCHEMBL954057 | 0.81 | EPHX1 (0.49) | EPHX1EPHX2SCN10AALDH1A1PDE2A | |
| SCHEMBL378939 | 0.80 | ALDH1A1 (0.50) | EPHX2ALDH1A1PDE2ATRPV1KMT2A | |
| Hydrochloric Acid SCHEMBL28755364 | 0.79 | EPHX1 (0.48) | EPHX1EPHX2SCN10AALDH1A1PDE2A | |
| SCHEMBL27181204 | 0.79 | EPHX1 (0.54) | EPHX1EPHX2SCN10AALDH1A1PDE2A | |
| SCHEMBL27175927 | 0.79 | CES2 (0.48) | EPHX1KMT2A | |
| SCHEMBL22758079 | 0.78 | EPHX1 (0.52) | EPHX1EPHX2SCN10AALDH1A1PDE2A | |
| SCHEMBL1938686 | 0.78 | POLB (0.52) | EPHX1EPHX2ALDH1A1PDE2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077701-A4 | ANTI-VIRAL COMPOUNDS | LILLY CO ELI (US) | 2002-03-20 | — | — | EP | disclosed |
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |
| EP-1077701-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059587-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-11-25 | — | — | WO | disclosed |