Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | PDE5A | O76074 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473060 | 0.90 | STAT1 (0.64) | STAT1MAPK1PDE5AHTTRAF1 | |
| SCHEMBL7470716 | 0.84 | STAT1 (0.42) | STAT1MAPK1PDE5AHTTMEN1 | |
| SCHEMBL7465501 | 0.83 | STAT1 (0.56) | STAT1MAPK1PDE5AHTTRAF1 | |
| SCHEMBL7466553 | 0.82 | STAT1 (0.52) | STAT1MAPK1PDE5AHTTRAF1 | |
| SCHEMBL7470701 | 0.81 | PDE5A (0.56) | STAT1MAPK1PDE5AHTTRAF1 | |
| SCHEMBL7464129 | 0.81 | MAPK1 (0.69) | STAT1MAPK1PDE5AHTTMEN1 | |
| SCHEMBL4725990 | 0.80 | MAPK1 (0.59) | STAT1MAPK1PDE5AHTTRAF1 | |
| SCHEMBL7474668 | 0.80 | HTT (0.63) | MAPK1PDE5AHTTMEN1KMT2A | |
| SCHEMBL7470639 | 0.80 | STAT1 (0.52) | STAT1MAPK1PDE5AHTTRAF1 | |
| SCHEMBL4728689 | 0.80 | PDE5A (0.55) | STAT1MAPK1PDE5AHTTRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |