Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | EGFR | P00533 | 7/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PDE5A | O76074 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465161 | 0.90 | PDE5A (0.52) | HTTMEN1KMT2AEGFRMAPK1 | |
| SCHEMBL7470418 | 0.89 | MAPK1 (0.65) | HTTMEN1KMT2AEGFRMAPK1 | |
| SCHEMBL7465009 | 0.88 | HTT (0.57) | HTTMEN1KMT2AEGFRMAPK1 | |
| SCHEMBL7473179 | 0.88 | MAPK1 (0.58) | HTTEGFRMAPK1LMNA | |
| SCHEMBL7473060 | 0.88 | STAT1 (0.64) | HTTMEN1KMT2AEGFRMAPK1 | |
| SCHEMBL7472725 | 0.87 | EGFR (0.61) | HTTEGFRMAPK1 | |
| SCHEMBL7475448 | 0.86 | EGFR (0.56) | HTTEGFRKDM4ESMN1; SMN2LMNA | |
| SCHEMBL7473897 | 0.86 | EGFR (0.55) | HTTEGFRNR2F2MAPK1 | |
| SCHEMBL7461665 | 0.86 | USP10 (0.59) | HTTMEN1KMT2AEGFRMAPK1 | |
| SCHEMBL7475194 | 0.86 | EGFR (0.66) | HTTEGFRNR2F2MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |