Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | STAT3 | P40763 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | APP | P05067 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | GALR3 | O60755 | 2/20 | 0.53 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | PDE5A | O76074 | 1/20 | 0.53 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473060 | 0.90 | STAT1 (0.64) | MAPK1SMN1; SMN2MEN1STAT3KMT2A | |
| SCHEMBL7465161 | 0.88 | PDE5A (0.52) | MAPK1SMN1; SMN2MEN1STAT3KMT2A | |
| SCHEMBL7467508 | 0.86 | MAPK1 (0.52) | MAPK1SMN1; SMN2MEN1STAT3KMT2A | |
| SCHEMBL7475626 | 0.85 | HTT (0.52) | MAPK1SMN1; SMN2MEN1STAT3KMT2A | |
| SCHEMBL7469664 | 0.85 | HTT (0.63) | MAPK1MEN1KMT2AMAPTHTT | |
| SCHEMBL7465156 | 0.85 | MAPK1 (0.53) | MAPK1SMN1; SMN2MEN1STAT3KMT2A | |
| SCHEMBL7469795 | 0.84 | EGFR (0.60) | MAPK1SMN1; SMN2MEN1STAT3KMT2A | |
| SCHEMBL7465501 | 0.83 | STAT1 (0.56) | MAPK1MEN1KMT2AHTTLMNA | |
| SCHEMBL7474665 | 0.83 | HTT (0.62) | MAPK1SMN1; SMN2MEN1STAT3KMT2A | |
| SCHEMBL7464363 | 0.83 | HTT (0.54) | MAPK1SMN1; SMN2MEN1STAT3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |