SCHEMBL7473544

SCHEMBL7473544

CC(N)Cc1cccc(Br)c1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PNMT P11086 2/20 0.60
TAAR1 Q96RJ0 6/20 0.59
SLC6A2 P23975 2/20 0.59
MAOA P21397 2/20 0.59
SIGMAR1 Q99720 2/20 0.59
SLC6A4 P31645 1/20 0.59
SLC6A3 Q01959 1/20 0.59
CYP2A6 P11509 1/20 0.59
ADORA2A P29274 1/20 0.59
ADORA1 P30542 1/20 0.59
HTR2A P28223 2/20 0.55
HTR2C P28335 2/20 0.55
HTR2B P41595 2/20 0.55
IDO1 P14902 2/20 0.52
AGXT P21549 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21583913 1.00 PNMT (0.60) PNMTTAAR1SLC6A2MAOASIGMAR1
SCHEMBL30174362 1.00 PNMT (0.60) PNMTTAAR1SLC6A2MAOASIGMAR1
SCHEMBL30457687 1.00 PNMT (0.60) PNMTTAAR1SLC6A2MAOASIGMAR1
Hydrochloric Acid SCHEMBL5234146 0.98 PNMT (0.58) PNMTTAAR1SLC6A2MAOASIGMAR1
Hydrochloric Acid SCHEMBL30559563 0.98 PNMT (0.58) PNMTTAAR1SLC6A2MAOASIGMAR1
SCHEMBL1513595 0.85 SIGMAR1 (0.53) TAAR1SIGMAR1IDO1AGXT
SCHEMBL30138659 0.85 SIGMAR1 (0.53) TAAR1SIGMAR1IDO1AGXT
SCHEMBL24152546 0.84 TAAR1 (0.73) PNMTTAAR1SLC6A2MAOASIGMAR1
SCHEMBL13387614 0.84 TAAR1 (0.73) PNMTTAAR1SLC6A2MAOASIGMAR1
SCHEMBL15487598 0.83 TAAR1 (0.46) PNMTTAAR1SLC6A2MAOASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023107715-A1 SPECIALIZED COMBINATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT TACTOGEN INC (US) 2023-06-15 WO claimed
CN-113963184-A Method for evaluating similarity of laser point cloud scene 杭州大数云智科技有限公司 2022-01-21 CN claimed
CN-121226008-A Bismuth ferrite-barium titanate-based energy storage material for pulse power element of new energy automobile electric control system and preparation method 常州大学 2025-12-30 CN disclosed
US-12459877-B1 Recyclable catalyst for carbon dioxide capture KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2025-11-04 US disclosed
CN-120166337-A Vibration device and device comprising a vibration device 乐金显示有限公司 2025-06-17 CN disclosed
CN-113735672-B Preparation method of fully substituted 1-butene-3-alkyne derivative 昆明理工大学 2025-01-21 CN disclosed
CN-118450787-A Piezoelectric device and apparatus including the same 乐金显示有限公司 2024-08-06 CN disclosed
CN-118284305-A Piezoelectric device and apparatus including the same 乐金显示有限公司 2024-07-02 CN disclosed
US-20240208932-A1 ARYLAMINO DERIVATIVE ESTROGEN RECEPTOR MODULATOR AND USE THEREOF XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) 2024-06-27 US disclosed
EP-4371977-A1 ARYLAMINO DERIVATIVE ESTROGEN RECEPTOR MODULATOR AND USE THEREOF Xizang Haisco Pharmaceutical Co., Ltd. (CN) 2024-05-22 EP disclosed
WO-2023107715-A1 SPECIALIZED COMBINATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT TACTOGEN INC (US) 2023-06-15 WO disclosed
US-20150210682-A1 Novel dihydroquinolizinones for the treatment and prophylaxis of hepatitis B virus infection HOFFMANN-LA ROCHE INC. (US) 2015-07-30 US disclosed
US-20150210682-A1 Novel dihydroquinolizinones for the treatment and prophylaxis of hepatitis B virus infection HOFFMANN-LA ROCHE INC. (US) 2015-07-30 US disclosed
US-20150210682-A1 Novel dihydroquinolizinones for the treatment and prophylaxis of hepatitis B virus infection HOFFMANN-LA ROCHE INC. (US) 2015-07-30 US disclosed
WO-2013040790-A1 SUBSTITUTED PYRIMIDINES MERCK SHARP & DOHME CORP. (US) 2013-03-28 WO disclosed
CN-1694870-A Acetyl 2-hydroxy-1, 3-diaminoalkanes PHARMACIA & UPJOHN CO LLC (US) 2005-11-09 CN disclosed
EP-1177175-A2 HETEROSUBSTITUTED PYRIDINE DERIVATIVES AS PDE 4 INHIBITORS MERCK FROSST CANADA INC. (CA) 2002-02-06 EP disclosed
WO-2000068198-A2 HETEROSUBSTITUTED PYRIDINE DERIVATIVES AS PDE 4 INHIBITORS MERCK FROSST CANADA & CO. (CA) 2000-11-16 WO disclosed
US-4857553-A SIDE EFFECT REDUCTION A. H. ROBINS COMPANY, INCORPORATED (US) 1989-08-15 US disclosed
EP-0302757-A2 Anti-emetic serotonin depleting agents A.H. ROBINS COMPANY, INCORPORATED (US) 1989-02-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240208932-A1 ARYLAMINO DERIVATIVE ESTROGEN RECEPTOR MODULATOR AND USE THEREOF GPER1, ESR1, ESRRA PNMT 2191/4885TAAR1 511/4885SLC6A2 2195/4885
US-20150210682-A1 Novel dihydroquinolizinones for the treatment and prophylaxis of hepatitis B virus infection HAVCR2, HCCS, DHX15 PNMT 4271/4885TAAR1 2895/4885SLC6A2 4575/4885
US-12459877-B1 Recyclable catalyst for carbon dioxide capture SCO2, TELO2, HAO2 PNMT 3469/4885TAAR1 514/4885SLC6A2 2628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.