Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NOS2 | P35228 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7054704 | 0.90 | ALDH1A1 (0.45) | NPC1RAB9AHTTALDH1A1KDM4E | |
| SCHEMBL382148 | 0.86 | MAPT (0.46) | NPC1RAB9ANOS2HTTALDH1A1 | |
| SCHEMBL7461740 | 0.84 | CDK1 (0.43) | NPC1RAB9ANOS2ALDH1A1KDM4E | |
| SCHEMBL7469397 | 0.79 | NOS2 (0.56) | NPC1RAB9ANOS2HTTALDH1A1 | |
| SCHEMBL7466043 | 0.78 | OPRK1 (0.43) | RAB9ANOS2HTTALDH1A1KDM4E | |
| SCHEMBL7470661 | 0.75 | OPRK1 (0.42) | RAB9ANOS2HTTALDH1A1MAPT | |
| SCHEMBL7050641 | 0.75 | OPRK1 (0.42) | RAB9ANOS2HTTALDH1A1MAPT | |
| SCHEMBL7471282 | 0.74 | AXL (0.46) | NPC1RAB9AHTTALDH1A1KDM4E | |
| SCHEMBL7051580 | 0.74 | HPGD (0.50) | NPC1RAB9AHTTALDH1A1MAPT | |
| SCHEMBL21135465 | 0.73 | HPGD (0.49) | NPC1RAB9AHTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |