Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | FPR3 | P25089 | 2/20 | 0.43 |
| ▸ | FPR2 | P25090 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 7/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484148 | 0.96 | KDM4E (0.50) | KDM4EFPR3FPR2ACHEHRH3 | |
| SCHEMBL8175564 | 0.92 | L3MBTL1 (0.41) | KDM4EFPR3FPR2ACHEMAPT | |
| SCHEMBL7474634 | 0.91 | MAPT (0.49) | KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL7472631 | 0.90 | MAPT (0.49) | KDM4EMAPT | |
| SCHEMBL7479943 | 0.90 | GNAI3 (0.42) | ACHEMAPTGNAI3GNAO1GNAI1 | |
| SCHEMBL7484189 | 0.89 | MAPT (0.49) | KDM4EMAPT | |
| SCHEMBL7472666 | 0.88 | ACHE (0.40) | ACHE | |
| SCHEMBL7475420 | 0.88 | KDM4E (0.46) | KDM4EBCHERAD52MAPTTP53 | |
| SCHEMBL7479747 | 0.87 | ACHE (0.39) | KDM4EACHE | |
| Hydrochloric Acid SCHEMBL7478950 | 0.87 | ACHE (0.39) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |