Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474634 | 0.96 | MAPT (0.49) | MAPTKDM4EALDH1A1CYP2C9EPHX1 | |
| Hydrochloric Acid SCHEMBL7472631 | 0.95 | MAPT (0.49) | MAPTKDM4EALDH1A1CYP2C9EPHX1 | |
| SCHEMBL7484148 | 0.93 | KDM4E (0.50) | MAPTKDM4EALDH1A1 | |
| SCHEMBL7471618 | 0.89 | KDM4E (0.45) | MAPTKDM4E | |
| SCHEMBL7475713 | 0.89 | MAPT (0.49) | MAPTKDM4EMMP3CYP2C9TDP1 | |
| SCHEMBL7479657 | 0.86 | MAPT (0.49) | MAPTALDH1A1CYP2C9EPHX1GAA | |
| SCHEMBL7473570 | 0.86 | MAPT (0.49) | MAPTALDH1A1CYP2C9EPHX1GAA | |
| SCHEMBL8175564 | 0.86 | L3MBTL1 (0.41) | MAPTKDM4EGAA | |
| SCHEMBL7479943 | 0.85 | GNAI3 (0.42) | MAPTCYP2C9 | |
| Hydrochloric Acid SCHEMBL7480498 | 0.85 | MAPT (0.48) | MAPTALDH1A1CYP2C9EPHX1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |