Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3068154 | 0.83 | TSHR (0.66) | RPS6KB1ROCK1PTGS2SMN1; SMN2L3MBTL1 | |
| SCHEMBL4096979 | 0.75 | RPS6KB1 (0.54) | RPS6KB1ROCK1SMN1; SMN2L3MBTL1TP53 | |
| SCHEMBL14364624 | 0.71 | RPS6KB1 (1.00) | RPS6KB1ROCK1PTGS2SMN1; SMN2LMNA | |
| SCHEMBL9954370 | 0.71 | L3MBTL1 (0.51) | L3MBTL1TP53LMNANPC1MAPT | |
| SCHEMBL28181208 | 0.71 | MGLL (0.47) | L3MBTL1MAPTMEN1KMT2AHTT | |
| SCHEMBL12730136 | 0.71 | MAPK1 (0.61) | RPS6KB1ROCK1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL10563532 | 0.70 | SMN1; SMN2 (0.47) | SMN1; SMN2TP53RAB9ALMNANPC1 | |
| SCHEMBL3967680 | 0.69 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9ALMNANPC1MAPT | |
| SCHEMBL4083024 | 0.69 | L3MBTL1 (0.56) | PTGS2SMN1; SMN2L3MBTL1TP53RAB9A | |
| SCHEMBL8593864 | 0.69 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1TP53LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998015551-A1 | QUINUCLIDINE DERIVATIVES AS ANTAGONISTS OF MUSCARINIC RECEPTORS | SYNTHELABO (FR) | 1998-04-16 | — | — | WO | disclosed |
| WO-1998004546-A1 | BENZIMIDAZOLE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTICAL USES THEREOF | SYNTHELABO (FR) | 1998-02-05 | — | — | WO | disclosed |