Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GGT1 | P19440 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471949 | 0.86 | HSD17B10 (0.42) | ALDH1A1PTGS2KDM4EHSD17B10TSHR | |
| SCHEMBL7476821 | 0.84 | SMN1; SMN2 (0.42) | ALDH1A1RECQLSMN1; SMN2HSD17B10TSHR | |
| SCHEMBL7476286 | 0.83 | ALDH1A1 (0.36) | ALDH1A1RECQLSMN1; SMN2HSD17B10PTGS1 | |
| SCHEMBL7471763 | 0.76 | ALDH1A1 (0.46) | ALDH1A1RECQLSMN1; SMN2KDM4ETSHR | |
| SCHEMBL6176436 | 0.75 | PTGS2 (0.47) | ALDH1A1PTGS2KDM4EHSD17B10TSHR | |
| SCHEMBL1452054 | 0.72 | PTGS2 (0.47) | ALDH1A1RECQLPTGS2KDM4EHSD17B10 | |
| SCHEMBL7474651 | 0.71 | MAPK1 (0.43) | ALDH1A1SMN1; SMN2KDM4EHSD17B10HPGD | |
| SCHEMBL7474112 | 0.71 | L3MBTL1 (0.37) | ALDH1A1RECQLSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9672920 | 0.70 | PTGS2 (0.46) | ALDH1A1PTGS2KDM4EHSD17B10TSHR | |
| SCHEMBL7469630 | 0.70 | KDM4E (0.42) | ALDH1A1RECQLSMN1; SMN2PTGS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194417-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AG (DE) | 2002-04-10 | — | — | EP | claimed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | claimed |
| EP-1194417-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AG (DE) | 2002-04-10 | — | — | EP | disclosed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | disclosed |