Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462130 | 0.91 | MAPT (0.42) | LMNASMN1; SMN2HTTALDH1A1MAPK1 | |
| SCHEMBL7459038 | 0.82 | MAPT (0.43) | LMNASMN1; SMN2ALDH1A1MAPK1MAPT | |
| SCHEMBL7469778 | 0.81 | MAPT (0.45) | LMNASMN1; SMN2HTTALDH1A1KDM4E | |
| SCHEMBL7470183 | 0.80 | MAPT (0.42) | LMNASMN1; SMN2ALDH1A1KDM4ETSHR | |
| SCHEMBL7468826 | 0.79 | EGFR (0.56) | LMNASMN1; SMN2HTTALDH1A1KDM4E | |
| SCHEMBL7474845 | 0.79 | LMNA (0.55) | LMNASMN1; SMN2PIK3CDPIK3R1HTT | |
| SCHEMBL7468270 | 0.79 | MAPT (0.40) | LMNASMN1; SMN2ALDH1A1MAPK1MAPT | |
| SCHEMBL7475788 | 0.79 | MAPT (0.40) | LMNASMN1; SMN2ALDH1A1MAPK1MAPT | |
| SCHEMBL7476091 | 0.78 | ACHE (0.54) | LMNASMN1; SMN2HTTHIF1AALDH1A1 | |
| SCHEMBL7466158 | 0.78 | HTR6 (0.55) | LMNASMN1; SMN2PIK3CDPIK3R1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |