SCHEMBL8415341

SCHEMBL8415341

CC1(C)CC(OCc2ccccc2)CC(C)(C)N1OCC1CO1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 2/20 0.40
PRMT6 Q96LA8 2/20 0.40
TMEM97 Q5BJF2 1/20 0.40
SIGMAR1 Q99720 1/20 0.40
PRMT8 Q9NR22 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
CTSL P07711 1/20 0.39
CTSB P07858 1/20 0.39
CTSK P43235 1/20 0.39
OPRM1 P35372 2/20 0.39
OPRL1 P41146 2/20 0.39
TDP1 Q9NUW8 1/20 0.38
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
TSHR P16473 2/20 0.36
DPP4 P27487 1/20 0.36
ALDH1A1 P00352 2/20 0.35
GLA P06280 1/20 0.35
MGLL Q99685 2/20 0.35
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9440082 0.85 CARM1 (0.46) CARM1PRMT6TMEM97SIGMAR1PRMT8
SCHEMBL7475314 0.84 CARM1 (0.45) CARM1PRMT6TMEM97SIGMAR1PRMT8
SCHEMBL9240294 0.82 CARM1 (0.44) CARM1PRMT6TMEM97SIGMAR1PRMT8
SCHEMBL8384384 0.82 OPRM1 (0.43) CARM1PRMT6TMEM97SIGMAR1PRMT8
SCHEMBL9335197 0.80 CARM1 (0.42) CARM1PRMT6TMEM97SIGMAR1PRMT8
SCHEMBL7771026 0.76 TDP1 (0.40) TMEM97SIGMAR1TDP1KMT2AMEN1
SCHEMBL9674864 0.76 CARM1 (0.48) CARM1PRMT6TMEM97SIGMAR1PRMT8
SCHEMBL562023 0.75 GAA (0.48) CARM1PRMT6TMEM97SIGMAR1PRMT8
SCHEMBL1150161 0.75 CTSL (0.46) CARM1PRMT6TMEM97SIGMAR1PRMT8
SCHEMBL7476490 0.75 CARM1 (0.36) CARM1PRMT6TMEM97SIGMAR1PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0634450-B1 Polyether with releasably bound sterically hindered amines as stabilizing agents CIBA GEIGY AG (CH) 1999-09-08 EP disclosed
US-5534618-A Polyethers containing hindered amines which can be cleaved off as stabilizers CIBA-GEIGY CORPORATION (US) 1996-07-09 US disclosed
EP-0634450-A2 Polyether with releasably bound sterically hindered amines as stabilizing agents CIBA-GEIGY AG (CH) 1995-01-18 EP disclosed