Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 3/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.32 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973515 | 0.93 | AVPR2 (0.37) | MAP3K7RXFP1JAK2AVPR2AVPR1A | |
| SCHEMBL7475173 | 0.91 | AVPR2 (0.32) | MAP3K7RXFP1AVPR2AVPR1AAVPR1B | |
| Hydrochloric Acid SCHEMBL7971911 | 0.87 | MAP3K7 (0.35) | MAP3K7AVPR2AVPR1AAVPR1BADRA1D | |
| SCHEMBL7964892 | 0.85 | AVPR2 (0.35) | MAP3K7RXFP1JAK2AVPR2AVPR1A | |
| SCHEMBL7474244 | 0.85 | AVPR2 (0.33) | MAP3K7RXFP1AVPR2AVPR1AAVPR1B | |
| SCHEMBL7970296 | 0.84 | MAP3K7 (0.36) | MAP3K7AVPR2AVPR1AAVPR1BIRAK4 | |
| SCHEMBL7478471 | 0.84 | MAP3K7 (0.36) | MAP3K7AVPR2AVPR1AAVPR1BADRA1D | |
| SCHEMBL7955154 | 0.84 | ADRA1D (0.32) | MAP3K7RXFP1AVPR2AVPR1AAVPR1B | |
| SCHEMBL7969562 | 0.83 | MAPK11 (0.36) | MAP3K7ADRA1DADRA1AADRA1BEPHX2 | |
| SCHEMBL7962351 | 0.83 | AVPR2 (0.37) | AVPR2AVPR1AAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316482-B1 | FOR THERAPY AND PROPHYLAXIS OF HYPERTENSION, HEART FAILURE, RENAL INSUFFICIENCY, EDEMA, ASCITES, VASOPRESSIN PARASECRETION SYNDROME, HEPATOCIRRHOSIS, HYPONATREMIA, HYPOKALEMIA, DIABETIC, CIRCULATION DISORDER, CEREBROVASCULAR DISEASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |
| EP-0946519-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024771-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-11 | — | — | WO | disclosed |