Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | ARG1 | P05089 | 2/20 | 0.35 |
| ▸ | ARG2 | P78540 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4332705 | 0.77 | GGT1 (0.52) | SLC1A3SLC1A2SLC1A1ARG1ARG2 | |
| SCHEMBL27598551 | 0.77 | GGT1 (0.52) | SLC1A3SLC1A2SLC1A1ARG1ARG2 | |
| SCHEMBL7474935 | 0.77 | L3MBTL1 (0.37) | L3MBTL1CA1 | |
| SCHEMBL2748871 | 0.76 | L3MBTL1 (0.38) | L3MBTL1SLC1A3SLC1A2SLC1A1CA1 | |
| SCHEMBL4918426 | 0.76 | GRM2 (0.44) | SLC1A3SLC1A2ARG1ARG2GRM2 | |
| SCHEMBL29353375 | 0.76 | GRM2 (0.44) | SLC1A3SLC1A2ARG1ARG2GRM2 | |
| SCHEMBL2033747 | 0.76 | TET2 (0.41) | L3MBTL1SLC1A3SLC1A2SLC1A1CA1 | |
| SCHEMBL4918433 | 0.76 | GRM2 (0.44) | SLC1A3SLC1A2ARG1ARG2GRM2 | |
| SCHEMBL5696063 | 0.76 | SLC1A3 (0.34) | SLC1A3SLC1A2SLC1A1ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL8028016 | 0.75 | L3MBTL1 (0.39) | L3MBTL1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864349-A2 | DYNAMIC BIOMIMETIC SYNZYME CATALYST, CATALYSIS, AND CATALYTIC SYSTEMS | The Regents of The University of California (US) | 2015-04-29 | — | — | EP | disclosed |
| WO-2013192430-A2 | DYNAMIC BIOMIMETIC SYNZYME CATALYST, CATALYSIS, AND CATALYTIC SYSTEMS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-12-27 | — | — | WO | disclosed |
| EP-1192162-A2 | TAXANE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | INDENA S.p.A. (IT) | 2002-04-03 | — | — | EP | disclosed |
| WO-2001002407-A2 | TAXANE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | INDENA S.P.A. (IT) | 2001-01-11 | — | — | WO | disclosed |
| US-4857650-A | Novel renin inhibitory amino acid derivatives | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| US-4725583-A | ANTIHYPERTENSIVE | ABBOTT LABORATORIES (US) | 1988-02-16 | — | — | US | disclosed |
| EP-0228192-A2 | Renin-inhibitory oligopeptides, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-07-08 | — | — | EP | disclosed |