SCHEMBL7474935

SCHEMBL7474935

COC(=O)C(N)(O)CCC(C)C

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.37
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
CA1 P00915 2/20 0.31
USP2 O75604 1/20 0.30
LMNA P02545 1/20 0.30
ANPEP P15144 2/20 0.30
RNPEP Q9H4A4 2/20 0.30
DNPEP Q9ULA0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7511783 0.82 L3MBTL1 (0.34) L3MBTL1HPGDHTTCA1ANPEP
SCHEMBL27291788 0.81 DGAT1 (0.35) L3MBTL1HPGDHTTCA1
SCHEMBL232278 0.77 L3MBTL1 (0.36) L3MBTL1CA1
SCHEMBL7475381 0.77 L3MBTL1 (0.36) L3MBTL1CA1
SCHEMBL13684875 0.75 CCR2 (0.37) L3MBTL1CA1
Hydrochloric Acid SCHEMBL8028016 0.74 L3MBTL1 (0.39) L3MBTL1CA1
SCHEMBL27593964 0.73 ODC1 (0.38) LMNA
SCHEMBL27726679 0.73 L3MBTL1 (0.34) L3MBTL1CA1USP2LMNA
SCHEMBL231232 0.73 DGAT1 (0.34) L3MBTL1CA1
SCHEMBL9101886 0.73 DGAT1 (0.44) CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1192162-A2 TAXANE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF INDENA S.p.A. (IT) 2002-04-03 EP disclosed
WO-2001002407-A2 TAXANE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF INDENA S.P.A. (IT) 2001-01-11 WO disclosed