Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478269 | 0.86 | MMP3 (0.57) | MMP3NPC1RAB9ACA12CA9 | |
| SCHEMBL14452195 | 0.85 | MMP3 (0.56) | MMP3NPC1RAB9ACA12CA9 | |
| SCHEMBL15672917 | 0.81 | ALDH1A1 (0.52) | MMP3NPC1RAB9ACA12CA9 | |
| SCHEMBL12305028 | 0.81 | ALDH1A1 (0.52) | MMP3NPC1RAB9ACA12CA9 | |
| SCHEMBL14452158 | 0.80 | HSD11B1 (0.56) | MMP3NPC1RAB9AALDH1A1POLB | |
| SCHEMBL14452142 | 0.79 | HSD11B1 (0.55) | MMP3POLBKMT2A | |
| SCHEMBL7282283 | 0.79 | MMP3 (0.50) | MMP3NPC1RAB9ACA12CA9 | |
| SCHEMBL7282278 | 0.79 | MMP3 (0.50) | MMP3NPC1RAB9ACA12CA9 | |
| SCHEMBL25566168 | 0.79 | MMP3 (0.49) | MMP3NPC1RAB9ACA12CA9 | |
| SCHEMBL7310016 | 0.78 | MMP3 (0.55) | MMP3POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104003913-B | The preparation method of E-3,4-dihydroxyphenyl vinylic sulfonamides and sulfonates compounds and the application as neuroprotective thereof | PEKING UNIVERSITY (CN) | 2015-10-07 | — | — | CN | disclosed |
| EP-0975594-B1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES | PFIZER LTD (GB) | 2002-09-18 | — | — | EP | disclosed |
| US-6281357-B1 | HEADACHE THERAPY | PFIZER INC | 2001-08-28 | — | — | US | disclosed |
| EP-0975594-A1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES | Pfizer Limited (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1999002493-A1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES | PFIZER LIMITED (GB) | 1999-01-21 | — | — | WO | disclosed |