Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | NAAA | Q02083 | 10/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472834 | 0.90 | S1PR1 (0.47) | S1PR1S1PR3S1PR5S1PR4 | |
| Hydrochloric Acid SCHEMBL7483274 | 0.89 | S1PR1 (0.47) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL7474468 | 0.86 | S1PR1 (0.46) | NAAAS1PR1S1PR3S1PR5HSD17B10 | |
| SCHEMBL7475716 | 0.76 | SIGMAR1 (0.44) | SIGMAR1S1PR1S1PR3S1PR5FKBP1A | |
| SCHEMBL8168786 | 0.76 | POLB (0.48) | EPHX1FKBP1A | |
| SCHEMBL7472666 | 0.75 | ACHE (0.40) | — | |
| SCHEMBL7479926 | 0.74 | MEN1 (0.45) | — | |
| SCHEMBL7470070 | 0.74 | MEN1 (0.45) | — | |
| SCHEMBL8180891 | 0.74 | MEN1 (0.45) | — | |
| Hydrochloric Acid SCHEMBL7478950 | 0.74 | ACHE (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |