Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 14/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7483274 | 0.99 | S1PR1 (0.47) | S1PR1S1PR3S1PR5S1PR4OPRD1 | |
| SCHEMBL7474468 | 0.96 | S1PR1 (0.46) | S1PR1S1PR3S1PR5S1PR4OPRD1 | |
| SCHEMBL7475719 | 0.90 | SIGMAR1 (0.42) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL7472666 | 0.85 | ACHE (0.40) | ACHEDNM1 | |
| SCHEMBL7477717 | 0.84 | S1PR1 (0.50) | S1PR1S1PR3S1PR5S1PR4OPRD1 | |
| SCHEMBL7479926 | 0.84 | MEN1 (0.45) | ACHEDNM1 | |
| Hydrochloric Acid SCHEMBL7478950 | 0.84 | ACHE (0.39) | ACHEDNM1 | |
| SCHEMBL7470070 | 0.84 | MEN1 (0.45) | ACHEDNM1 | |
| SCHEMBL8180891 | 0.84 | MEN1 (0.45) | ACHEDNM1 | |
| SCHEMBL7470814 | 0.84 | ACHE (0.44) | ACHEDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |