Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505167 | 0.75 | MEN1 (1.00) | RAB9AMEN1KMT2ANR4A1SRD5A2 | |
| SCHEMBL11547434 | 0.73 | MEN1 (0.43) | MEN1KMT2ANR4A1MAPK1ALDH1A1 | |
| SCHEMBL10370580 | 0.72 | CA2 (0.53) | RAB9AMEN1KMT2ASRD5A2MAPK1 | |
| SCHEMBL7475836 | 0.71 | MEN1 (0.39) | RAB9AMEN1KMT2AMAPK1ALDH1A1 | |
| Potassium Ion SCHEMBL11502616 | 0.70 | ALDH1A1 (0.34) | MEN1KMT2ANR4A1MAPK1ALDH1A1 | |
| SCHEMBL7792236 | 0.70 | CNR2 (0.51) | RAB9AMEN1KMT2ANR4A1SRD5A2 | |
| SCHEMBL3467639 | 0.69 | MAPT (0.34) | MEN1KMT2AMAPK1ALDH1A1LMNA | |
| Ammonia Solution, Strong SCHEMBL11460421 | 0.69 | NR4A1 (0.57) | RAB9AMEN1KMT2ANR4A1SRD5A2 | |
| SCHEMBL4448099 | 0.69 | SRD5A2 (0.45) | RAB9AMEN1KMT2ANR4A1SRD5A2 | |
| SCHEMBL17927701 | 0.68 | KMT2A (0.50) | RAB9AMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894088-A4 | SUBSTITUTED SULFONIC ACID N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLAMIDE COMPOUNDS | RHONE POULENC RORER PHARMA (US) | 2001-12-05 | — | — | EP | disclosed |
| EP-0894088-A1 | SUBSTITUTED SULFONIC ACID N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1999-02-03 | — | — | EP | disclosed |
| WO-1998024784-A1 | SUBSTITUTED SULFONIC ACID N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-06-11 | — | — | WO | disclosed |