SCHEMBL7792236

SCHEMBL7792236

O=C(c1ccc(Cl)cc1)c1ccc(Cl)cc1S(=O)(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.51
SRD5A2 P31213 2/20 0.50
MAPT P10636 4/20 0.46
RAB9A P51151 3/20 0.46
NR4A1 P22736 1/20 0.46
MAPK1 P28482 2/20 0.44
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
POLB P06746 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
FLT1 P17948 1/20 0.41
FLT4 P35916 1/20 0.41
KDR P35968 1/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
ITGA1 P56199 1/20 0.40
NPC1 O15118 1/20 0.40
LMNA P02545 1/20 0.40
NFKB1 P19838 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7788627 0.92 MAPK1 (0.53) CNR2SRD5A2MAPTRAB9ANR4A1
SCHEMBL7788631 0.90 ALDH1A1 (0.49) SRD5A2MAPTNR4A1KMT2AITGA1
Ammonia Solution, Strong SCHEMBL11460421 0.81 NR4A1 (0.57) SRD5A2MAPTRAB9ANR4A1MAPK1
SCHEMBL3907824 0.80 CASP1 (0.57) SRD5A2MAPK1MEN1KMT2ATDP1
SCHEMBL7787703 0.77 NR4A1 (0.51) SRD5A2MAPTRAB9ANR4A1MAPK1
SCHEMBL7790459 0.76 ALDH1A1 (0.50) SRD5A2MAPTRAB9AMAPK1KMT2A
SCHEMBL8430986 0.76 RAPGEF4 (0.49) MAPTRAB9AMEN1KMT2APOLB
SCHEMBL250228 0.76 MMP2 (0.50) CNR2SRD5A2MAPK1MEN1KMT2A
SCHEMBL9496067 0.76 SRD5A2 (0.79) SRD5A2MAPTRAB9ANR4A1MAPK1
SCHEMBL5082270 0.75 MMP2 (0.49) CNR2SRD5A2MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3395323-B1 METHOD FOR TREATING HAIR KAO CORP (JP) 2021-09-29 EP disclosed
US-20190038532-A1 METHOD FOR TREATING HAIR KAO CORPORATION (JP) 2019-02-07 US disclosed
EP-3395323-A1 HAIR TREATMENT METHOD Kao Corporation (JP) 2018-10-31 EP disclosed
EP-0672405-B1 Hair treatment composition KAO CORP (JP) 2001-11-14 EP disclosed
EP-0743847-B1 HAIR COSMETIC COMPOSITION KAO CORP (JP) 2001-05-30 EP disclosed
US-6217855-B1 ELASTICITY KAO CORPORATION (JP) 2001-04-17 US disclosed
EP-0662314-B1 Method of hair treatment KAO CORP (JP) 1999-11-03 EP disclosed
US-5683685-A NAPHTHALENESULFONIC ACID AND/OR BENZOPHENONE SULFONIC ACID WITH ANIONIC AND/OR AMPHOTERIC SURFACTANT WITH OIL KAO CORPORATION (JP) 1997-11-04 US disclosed
EP-0743847-A1 HAIR COSMETIC COMPOSITION Kao Corporation (JP) 1996-11-27 EP disclosed
EP-0529437-B1 Hair treatment composition KAO CORP (JP) 1996-07-17 EP disclosed
EP-0672405-A1 Hair treatment composition KAO CORPORATION (JP) 1995-09-20 EP disclosed
WO-1995020375-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 1995-08-03 WO disclosed
EP-0662314-A1 Method of hair treatment Kao Corporation (JP) 1995-07-12 EP disclosed
EP-0529437-A1 Hair treatment composition Kao Corporation (JP) 1993-03-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190038532-A1 METHOD FOR TREATING HAIR TYR, POLR1C, CA7 CNR2 3545/4885SRD5A2 89/4885MAPT 1450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.