Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474197 | 0.87 | CES1 (1.00) | CES1ALDH1A1PRMT1TDP1CYP19A1 | |
| SCHEMBL6554630 | 0.87 | CES1 (1.00) | CES1ALDH1A1PRMT1TDP1CYP19A1 | |
| SCHEMBL6554559 | 0.85 | CES1 (0.73) | CES1ALDH1A1PRMT1TDP1CYP19A1 | |
| SCHEMBL7572500 | 0.85 | CES1 (0.73) | CES1ALDH1A1PRMT1TDP1CYP19A1 | |
| SCHEMBL11775495 | 0.83 | CA12 (0.64) | ALDH1A1TDP1HTTARMAPT | |
| SCHEMBL11774264 | 0.82 | KMT2A (0.69) | ALDH1A1CYP19A1PGRARMAPT | |
| SCHEMBL7364375 | 0.79 | ALDH1A1 (0.68) | ALDH1A1TDP1HTTMAPTCA1 | |
| SCHEMBL96121 | 0.79 | CES1 (0.81) | CES1ALDH1A1PRMT1TDP1CYP19A1 | |
| SCHEMBL2136408 | 0.79 | CES1 (0.81) | CES1ALDH1A1PRMT1TDP1CYP19A1 | |
| SCHEMBL6302309 | 0.79 | CES1 (0.81) | CES1ALDH1A1PRMT1TDP1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010011085-A1 | 4-SUBSTITUTED CEPHEM DERIVATIVES AS ELASTASE INHIBITORS | PHARMACIA & UPJOHN S.P.A. (IT) | 2001-08-02 | — | — | US | claimed |
| EP-0809644-A1 | 4-SUBSTITUTED CEPHEM DERIVATIVES AS ELASTASE INHIBITORS | PHARMACIA & UPJOHN S.p.A. (IT) | 1997-12-03 | — | — | EP | claimed |
| WO-1997022609-A1 | 4-SUBSTITUTED CEPHEM DERIVATIVES AS ELASTASE INHIBITORS | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-06-26 | — | — | WO | claimed |
| US-20010011085-A1 | 4-SUBSTITUTED CEPHEM DERIVATIVES AS ELASTASE INHIBITORS | PHARMACIA & UPJOHN S.P.A. (IT) | 2001-08-02 | — | — | US | disclosed |
| EP-0809644-A1 | 4-SUBSTITUTED CEPHEM DERIVATIVES AS ELASTASE INHIBITORS | PHARMACIA & UPJOHN S.p.A. (IT) | 1997-12-03 | — | — | EP | disclosed |
| WO-1997022609-A1 | 4-SUBSTITUTED CEPHEM DERIVATIVES AS ELASTASE INHIBITORS | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010011085-A1 | 4-SUBSTITUTED CEPHEM DERIVATIVES AS ELASTASE INHIBITORS | SERPINB1, ELANE, CTSE | CES1 81/4885ALDH1A1 3023/4885PRMT1 1562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.