SCHEMBL7475906

SCHEMBL7475906

c1csc(C2(c3cccs3)CCCO2)c1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.44
MEN1 O00255 1/20 0.43
PRCP P42785 1/20 0.43
KMT2A Q03164 1/20 0.43
SIGMAR1 Q99720 1/20 0.43
SLC6A3 Q01959 1/20 0.42
SLC6A4 P31645 1/20 0.40
OPRM1 P35372 2/20 0.39
OPRL1 P41146 2/20 0.39
ALDH1A1 P00352 1/20 0.38
LMNA P02545 2/20 0.37
TSHR P16473 1/20 0.37
ICMT O60725 1/20 0.36
OPRD1 P41143 1/20 0.34
OPRK1 P41145 1/20 0.34
TP53 P04637 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9773287 0.86 SLC6A3 (0.37) SLC6A2MEN1PRCPKMT2ASIGMAR1
SCHEMBL8613260 0.82 KMT2A (0.35) SLC6A2MEN1PRCPKMT2ASIGMAR1
SCHEMBL8615856 0.81 OPRM1 (0.37) SLC6A2MEN1PRCPKMT2ASIGMAR1
SCHEMBL9738374 0.81 SLC6A3 (0.44) SLC6A2MEN1PRCPKMT2ASIGMAR1
SCHEMBL1719841 0.74 SLC6A2 (0.44) SLC6A2MEN1PRCPKMT2ASIGMAR1
SCHEMBL8662680 0.74 SLC6A2 (0.33) SLC6A2MEN1PRCPKMT2ASIGMAR1
SCHEMBL7383033 0.74 ALDH1A1 (0.44) SLC6A2MEN1PRCPKMT2ASIGMAR1
SCHEMBL28983665 0.73 ICMT (0.46) SLC6A2MEN1PRCPKMT2ASIGMAR1
SCHEMBL1009254 0.72 SLC6A2 (0.45) SLC6A2MEN1PRCPKMT2ASIGMAR1
SCHEMBL754463 0.71 SLC6A3 (0.41) SLC6A2MEN1PRCPKMT2ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867437-B1 \"Method of preparing a thiophene-containing or furan -containing conjugated compound and precursor compound used therein\". KONINKL PHILIPS ELECTRONICS NV (NL) 2002-11-13 EP claimed
US-6184540-B1 SEMICONDUCTOR HAVING A LAYER OF A POLYTHIOPHENE DERIVED FROM A SOLUBLE PRECURSOR COMPOUND OF TETRAHYDROTHIOPHENE OR TETRAHYDROFURAN UNITS HAVING THERMALLY SEPARABLE ARYL- OR ALKYL-THIO SUBSTITUENTS, WHICH CAN BE PROCESSED FROM SOLUTION U.S. PHILIPS CORPORATION 2001-02-06 US claimed
US-6124475-A Method of preparing a thiophene-containing or furan-containing conjugated compound and precursor compound used therein U.S. PHILIPS CORPORATION (US) 2000-09-26 US claimed
US-5919951-A Method of preparing a thiophene-containing or furan-containing conjugated compound and precursor compound used therein U.S. PHILIPS CORPORATION (US) 1999-07-06 US claimed
EP-0867437-A1 \"Method of preparing a thiophene-containing or furan -containing conjugated compound and precursor compound used therein\". Koninklijke Philips Electronics N.V. (NL) 1998-09-30 EP claimed
EP-0867437-B1 \"Method of preparing a thiophene-containing or furan -containing conjugated compound and precursor compound used therein\". KONINKL PHILIPS ELECTRONICS NV (NL) 2002-11-13 EP disclosed
US-6184540-B1 SEMICONDUCTOR HAVING A LAYER OF A POLYTHIOPHENE DERIVED FROM A SOLUBLE PRECURSOR COMPOUND OF TETRAHYDROTHIOPHENE OR TETRAHYDROFURAN UNITS HAVING THERMALLY SEPARABLE ARYL- OR ALKYL-THIO SUBSTITUENTS, WHICH CAN BE PROCESSED FROM SOLUTION U.S. PHILIPS CORPORATION 2001-02-06 US disclosed
US-6124475-A Method of preparing a thiophene-containing or furan-containing conjugated compound and precursor compound used therein U.S. PHILIPS CORPORATION (US) 2000-09-26 US disclosed
US-5919951-A Method of preparing a thiophene-containing or furan-containing conjugated compound and precursor compound used therein U.S. PHILIPS CORPORATION (US) 1999-07-06 US disclosed
EP-0867437-A1 \"Method of preparing a thiophene-containing or furan -containing conjugated compound and precursor compound used therein\". Koninklijke Philips Electronics N.V. (NL) 1998-09-30 EP disclosed