Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 11/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555413 | 0.85 | HTT (0.52) | HTTSMN1; SMN2ALDH1A1TSHRPPARG | |
| SCHEMBL8552185 | 0.81 | PPARG (0.45) | HTTSMN1; SMN2ALDH1A1PPARG | |
| SCHEMBL7468634 | 0.79 | HTT (0.54) | HTTSMN1; SMN2ALDH1A1TSHRPPARG | |
| SCHEMBL8557139 | 0.76 | TP53 (0.42) | HTTSMN1; SMN2ALDH1A1PPARG | |
| SCHEMBL7467559 | 0.73 | TSHR (0.58) | HTTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7475652 | 0.72 | PPARG (0.61) | PPARG | |
| SCHEMBL14381314 | 0.71 | PPARG (0.62) | PPARG | |
| SCHEMBL8602166 | 0.70 | NPC1 (0.43) | HTTSMN1; SMN2ALDH1A1TSHRPPARG | |
| SCHEMBL7471998 | 0.69 | TSHR (0.48) | HTTSMN1; SMN2ALDH1A1TSHRPPARG | |
| SCHEMBL14507328 | 0.69 | PPARG (0.42) | HTTSMN1; SMN2ALDH1A1TSHRPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |