Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602170 | 0.82 | ALDH1A1 (0.39) | MEN1KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL7473593 | 0.72 | TSHR (0.61) | MEN1KMT2ASMN1; SMN2ALDH1A1SIRT1 | |
| SCHEMBL7469321 | 0.72 | TSHR (0.58) | MEN1KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL10192659 | 0.71 | MYC (0.51) | NPC1MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL14507328 | 0.70 | PPARG (0.42) | SMN1; SMN2ALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL9886623 | 0.66 | P2RX4 (0.57) | MEN1KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL8555413 | 0.66 | HTT (0.52) | SMN1; SMN2ALDH1A1SIRT1TSHRHTT | |
| SCHEMBL7465025 | 0.65 | TSHR (0.55) | NPC1MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL7468634 | 0.65 | HTT (0.54) | SMN1; SMN2ALDH1A1TSHRMAPK1HTT | |
| SCHEMBL7467559 | 0.65 | TSHR (0.58) | SMN1; SMN2ALDH1A1SIRT1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |