Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557139 | 0.86 | TP53 (0.42) | PPARGHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL8602443 | 0.83 | HTT (0.51) | PPARGHTTALDH1A1 | |
| SCHEMBL7475955 | 0.81 | HTT (0.55) | PPARGHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL8554310 | 0.80 | TSHR (0.48) | PPARGALDH1A1SMN1; SMN2 | |
| SCHEMBL8551698 | 0.80 | ALDH1A1 (0.45) | PPARGALDH1A1SMN1; SMN2 | |
| SCHEMBL8553942 | 0.77 | TSHR (0.46) | PPARGALDH1A1SMN1; SMN2 | |
| SCHEMBL8556015 | 0.75 | HTT (0.53) | PPARGHTT | |
| SCHEMBL8596034 | 0.75 | TSHR (0.48) | PPARGHTTALDH1A1 | |
| SCHEMBL8653249 | 0.75 | HTT (0.50) | HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL8644730 | 0.74 | PPARG (0.47) | PPARGHTTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |