Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | XIAP | P98170 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 12/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474325 | 0.82 | TSHR (0.65) | HTTXIAPPPARGTSHRALDH1A1 | |
| SCHEMBL7467559 | 0.81 | TSHR (0.58) | HTTTSHRMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7473032 | 0.80 | HTT (0.52) | HTTXIAPPPARGTSHRALDH1A1 | |
| SCHEMBL8555413 | 0.80 | HTT (0.52) | HTTPPARGTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7476860 | 0.79 | TSHR (0.64) | HTTPPARGTSHRMAPK1USP2 | |
| SCHEMBL7465025 | 0.79 | TSHR (0.55) | HTTTSHRMAPK1USP2ALDH1A1 | |
| SCHEMBL7471315 | 0.77 | ALDH1A1 (0.68) | HTTXIAPTSHRMAPK1USP2 | |
| SCHEMBL7473593 | 0.76 | TSHR (0.61) | HTTPPARGTSHRMAPK1ALDH1A1 | |
| SCHEMBL8552816 | 0.76 | PPARG (0.46) | XIAPPPARG | |
| SCHEMBL7473291 | 0.76 | TSHR (0.54) | HTTXIAPPPARGTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |